BONE MARROW NECROSIS IN SICKLE CELL DISEASE, A CLINICAL & PATHOLOGICAL STUDY
نویسندگان
چکیده
منابع مشابه
Bone marrow necrosis – initial presentation in sickle cell anemia
PATIENT Male, 20 FINAL DIAGNOSIS: Sickle cell anemia Symptoms: Bone marrow necrosis • bone pain • fever • hepatomegaly • icterus • splenomegaly • weakness MEDICATION - Clinical Procedure: - Specialty: Hematology. OBJECTIVE Unusual clinical course. BACKGROUND In sickle cell disease, bone involvement is the commonest clinical presentation in the acute as well as chronic setting presenting a...
متن کاملBone marrow necrosis and fat embolism syndrome: a dreadful complication of hemoglobin sickle cell disease
Sickle cell disease encompasses a wide range of genotypic presentation with particular clinical features. The entity affects millions of people, particularly those whose ancestors came from sub-Saharan Africa and other countries in the Western Hemisphere, Saudi Arabia, and India. Currently, the high frequency of S and C genes reflects natural selection through the protection of heterozygotes ag...
متن کاملFatal fungal superinfection complicating B19 virus-induced massive bone marrow necrosis in sickle-cell disease.
Manifestations of acute B19 virus infection in sickle cell disease range from transient and benign isolated anemia to life-threatening conditions. We report a case of a B19 virus-induced massive bone marrow necrosis with severe pancytopenia complicated by a fatal secondary acquired fungal superinfection. A 29-year old woman was admitted to hospital for dizziness, muscular and diffuse bone pain,...
متن کاملBone Marrow Necrosis: Frequency and clinicopathilogical Findings in Marrow Biopsyes
Background and Objectives: Bone marrow necrosis (BMN) is a rare and ominous complication of wide variety of diseases including hematologic malignancy. This study was performed to identify frequency and the underlying associated diseases of marrow necrosis. Materials and Methods: In this descriptive study, totally 850 bone marrow trephine biopsies related to living patients at the Pathology ...
متن کاملBone marrow transplantation in sickle cell anaemia.
Sickle cell anaemia is still responsible for severe crippling and death in young patients living in developing countries. Apart from prophylaxis and treatment of infections, no active treatment can be safely proposed in such areas of the world. Therefore a bone marrow transplantation was performed in 12 patients staying in Belgium and planning to return to Africa. Twelve patients, aged between ...
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ژورنال
عنوان ژورنال: Basrah Journal of Surgery
سال: 2007
ISSN: 2409-501X
DOI: 10.33762/bsurg.2007.56273